منابع مشابه
Osteosclerosis in myeloma.
In multiple myeloma the typical bone lesions are usually purely osteolytic and the presence of any osteosclerosis suggests that the diagnosis should be reconsidered. There have now been reports of forty-nine patients with myeloma with osteosclerotic deposits in whom radiotherapy could not be implicated as a cause (Kr , Wiedermann, Vykydal and Soyka 1967; Evison and Evans 1967; Osuntokun, Akinku...
متن کاملClostridial enteropathy in lactating outbred swiss-derived (ICR) mice.
Reports of severe enteric disease of unknown etiology affecting lactating mice have appeared in the literature. Clostridial disease similar to that seen in cattle and sheep on high-carbohydrate rations and caused by Clostridium perfringens has been suspected in these mouse outbreaks but has not been isolated from affected mice. The present report describes a severe, necrotizing enterocolitis as...
متن کاملPharmacokinetic interactions of flunixin meglumine and enrofloxacin in ICR mice.
We examined the pharmacokinetic interactions of enrofloxacin and flunixin in male ICR mice that were subcutaneously (SC) administered with both or either one of the drugs. The experiments were performed on the following three groups: flunixin alone (2 mg/kg, SC), combination of flunixin (2 mg/kg, SC) and enrofloxacin (10 mg/kg, SC), and enrofloxacin alone (10 mg/kg, SC). Blood samples were coll...
متن کاملCholesterol-Lowering Effect of Allicin on Hypercholesterolemic ICR Mice
Allicin was discussed as an active compound with regard to the beneficial effects of garlic in atherosclerosis. The aim of this study was to investigate the cholesterol-lowering properties of allicin. In order to examine its effects on hypercholesterolemia in male ICR mice, this compound with doses of 5, 10, or 20 mg/kg body weight was given orally daily for 12 weeks. Changes in body weight and...
متن کاملProteasome inhibitor bortezomib impairs both myelofibrosis and osteosclerosis induced by high thrombopoietin levels in mice.
Primary myelofibrosis (PMF) is the most serious myeloproliferative disorder, characterized by clonal myeloproliferation associated with cytokine-mediated bone marrow stromal reaction including fibrosis and osteosclerosis. Current drug therapy remains mainly palliative. Because the NF-kappaB pathway is implicated in the abnormal release of cytokines in PMF, the proteasome inhibitor bortezomib mi...
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ژورنال
عنوان ژورنال: The Japanese Journal of Veterinary Science
سال: 1985
ISSN: 0021-5295,1881-1442
DOI: 10.1292/jvms1939.47.799